Spectral domain optical coherence tomography in mouse models of retinal degeneration.

@article{Huber2009SpectralDO,
  title={Spectral domain optical coherence tomography in mouse models of retinal degeneration.},
  author={Gesine Huber and Susanne C Beck and Christian Grimm and Ayse Sahaboglu-Tekgoz and François Paquet-Durand and Andreas Wenzel and Peter Humphries and T Michael Redmond and Mathias Wolfgang Seeliger and Manuel Dominik Fischer},
  journal={Investigative ophthalmology & visual science},
  year={2009},
  volume={50 12},
  pages={5888-95}
}
PURPOSE Spectral domain optical coherence tomography (SD-OCT) allows cross-sectional visualization of retinal structures in vivo. Here, the authors report the efficacy of a commercially available SD-OCT device to study mouse models of retinal degeneration. METHODS C57BL/6 and BALB/c wild-type mice and three different mouse models of hereditary retinal degeneration (Rho(-/-), rd1, RPE65(-/-)) were investigated using confocal scanning laser ophthalmoscopy (cSLO) for en face visualization and SD… CONTINUE READING