Spectral assignment and cytotoxicity of 22-hydroxytingenone from Glyptopetalum sclerocarpum.

@article{Bavovada1990SpectralAA,
  title={Spectral assignment and cytotoxicity of 22-hydroxytingenone from Glyptopetalum sclerocarpum.},
  author={Rapepol Bavovada and G{\'a}bor Blask{\'o} and Hui Ling Shieh and John M Pezzuto and Geoffrey A. Cordell},
  journal={Planta medica},
  year={1990},
  volume={56 4},
  pages={
          380-2
        }
}
22-Hydroxytingenone was reisolated from a new source, Glyptopetalum sclerocarpum M. Laws and, for the first time, its unambiguous 13C-NMR assignments were accomplished through the use of APT, HETCOR, and selective INEPT spectroscopy. Intense, but nonspecific cytotoxic activity was observed when this substance was evaluated with a battery of cell lines comprised of the P-388 lymphocytic leukemia, KB carcinoma of the nasopharynx, and a number of human cancer cell types, i.e. HT-1080 fibrosarcoma… CONTINUE READING
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