Spectra library assisted de novo peptide sequencing for HCD and ETD spectra pairs

Abstract

De novo peptide sequencing via tandem mass spectrometry (MS/MS) has been developed rapidly in recent years. With the use of spectra pairs from the same peptide under different fragmentation modes, performance of de novo sequencing is greatly improved. Currently, with large amount of spectra sequenced everyday, spectra libraries containing tens of thousands… (More)
DOI: 10.1186/s12859-016-1330-0

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