Specimen shrinkage and its influence on margin assessment in breast cancer.

@article{Yeap2007SpecimenSA,
  title={Specimen shrinkage and its influence on margin assessment in breast cancer.},
  author={Badrul Hisham Yeap and Suseela Muniandy and Suk-Kam Lee and Subathra Sabaratnam and Manjit Kaur Doola Singh},
  journal={Asian journal of surgery},
  year={2007},
  volume={30 3},
  pages={183-7}
}
OBJECTIVE The determination of tumour-free margin in breast cancer is crucial in deciding subsequent patient management. To exemplify the phenomenon of margin contraction during specimen preparation for histopathological analysis, we quantified the shrinkage of breast specimens as a result of formalin fixation. METHODS Fifty consecutive mastectomy and wide excision specimens were prospectively appraised. The closest free margin and maximal tumour diameter of fresh, unprepared specimens were… CONTINUE READING

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