Specifying and protecting germ cell fate

@article{Strome2015SpecifyingAP,
  title={Specifying and protecting germ cell fate},
  author={Susan Strome and Dustin L Updike},
  journal={Nature Reviews Molecular Cell Biology},
  year={2015},
  volume={16},
  pages={406-416}
}
Germ cells are the special cells in the body that undergo meiosis to generate gametes and subsequently entire new organisms after fertilization, a process that continues generation after generation. Recent studies have expanded our understanding of the factors and mechanisms that specify germ cell fate, including the partitioning of maternally supplied 'germ plasm', inheritance of epigenetic memory and expression of transcription factors crucial for primordial germ cell (PGC) development. Even… CONTINUE READING
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