Specificity of the transport system for tricarboxylic acid cycle intermediates in renal brush borders

@article{Wright1980SpecificityOT,
  title={Specificity of the transport system for tricarboxylic acid cycle intermediates in renal brush borders},
  author={Stephen H. Wright and Ian Kippen and James R. Klinenberg and Ernest M Wright},
  journal={The Journal of Membrane Biology},
  year={1980},
  volume={57},
  pages={73-82}
}
Uptake studies employing renal brush border membranes were used to examine the structural specificity of the TCA cycle intermediate transport system. The kinetics of reciprocal inhibition between succinate and citrate revealed these compounds to be transported by a common mechanism. The Michaelis constant for succinate (0.11mm) was significantly lower than… CONTINUE READING