Specificity of the Stimulatory Effect of Betaine on the Vitamin B12 Fermentation

METHYL donors such as betaine and choline are known to stimulate production of vitamin B12 by certain microorganisms1. Ansbacher and Hill2 reported that of the crude microbial processes available in 1949, the best were characterized by disappearance of choline from the medium. Miller and Putter of these laboratories (unpublished) discovered that betaine and… CONTINUE READING