Specificity of the FTA-ABS and TPHA tests during pregnancy.
@article{ManikowskaLesiska1978SpecificityOT, title={Specificity of the FTA-ABS and TPHA tests during pregnancy.}, author={W Manikowska-Lesińska and B Linda and W. Zajac}, journal={The British Journal of Venereal Diseases}, year={1978}, volume={54}, pages={295 - 298} }
In order to determine whether pregnancy influences the specificity of the fluorescent treponemal antibody absorption (FTA-ABS) and Treponema palidum haemagglutination assay (TPHA) tests, these tests, together with the quantitative fluorescent treponemal antibody (FTA) and Venereal Disease Research Laboratory (VDRL) tests, were carried out simultaneously on 2000 pregnant women who attended for compulsory prenatal screening. In only one patient (0.05% of the total investigated) was a positive…
11 Citations
Non-specific positive test results to syphilis in dermatological diseases.
- MedicineThe British journal of venereal diseases
- 1980
The test producing the most non-specific results was the FTA test, followed by the FTA-ABS test, the VDRL test, and Kolmer's test; these were found more frequently in patients with pyodermas, neoplasms, acne, mycoses, crural ulceration, and psoriasis than in those with other diseases.
Fluorescent Treponemal Antibody‐Absorption (FTA‐ABS) Test
- Biology, MedicineInternational journal of dermatology
- 1982
The fluorescent treponemal antibody-absorption test was developed to avoid nonspecific positive reactions in the FTA-test, which is known as the ETA-.5 test, because test sera were used at a 1/5 dilution.
Depressed CD4/CD8 Ratio in TPHA‐Negative Patients with Syphilis
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- 1992
The experience with six elderly patients with syphilis, whose TPHA was negative, suggests that the TPHA is insufficient for excluding elderly syphilitics because of immunological impairment seen in aged patients.
Comparative evaluation of commercial fluorescent treponemal antibody-absorbed test kits
- BiologyJournal of clinical microbiology
- 1984
The development of an immunological standard for use in the manufacture of fluorescent treponemal antibody-absorbed test kits is recommended, with the goal of obtaining uniform performance characteristics among commercial test kits.
Syphilis tests in diagnostic and therapeutic decision making.
- Medicine, PsychologyAnnals of internal medicine
- 1986
Predictive value calculations were used to derive diagnostic guidelines for syphilis and screening of asymptomatic persons with the VDRL test, followed by treponemal test confirmation on positive sera, is recommended for all pregnant women, contacts of persons with infectious syphilis, and other high-risk groups.
Antenatal screening for syphilis at the University of Nigeria Teaching Hospital, Enugu, Nigeria — A six year survey
- MedicineInternational journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics
- 1989
Clinical Focus: Infections in Pregnancy
- MedicineHospital practice
- 2014
A review outlines the challenges associated with managing important infectious diseases in the pregnant population and references the most recent evidence and international treatment guidelines.
Obstetric infections.
- Medicine, BiologyThe Western journal of medicine
- 1981
Altered physiological and immunological states during pregnancy are important in understanding the pathophysiology of maternal infections.
Clinical Application Of Serological Tests For Syphilis SUMMARY
- Biology, Medicine
- 2008
The humoral response to T. pallidum invades the human host and multiple humoral antibodies are formed, of two types: antitreponemal antibodies and antibody-like substances known as reagin or lipoidal antibodies.
References
SHOWING 1-10 OF 34 REFERENCES
FTA-ABS Test in Pregnancy: A Probable False-Positive Reaction
- Medicine
- 1970
The fluorescent treponemal antibody absorption (FTA-ABS) test has gained wide acceptance as the standard by which the diagnosis of syphilis is confirmed and false-positive reactions to reagin tests…
The Treponema pallidum haemagglutination (TPHA) test in biological false positive and leprosy sera
- Medicine, BiologyJournal of clinical pathology
- 1973
It was concluded that where reagin and TPHA tests are reactive in a person who has no history or clinical signs of syphilis, the serum should be referred for TPI and FTA-ABS testing.
Spontaneous reversion of FTA-ABS test reactions.
- MedicineJAMA
- 1975
In a series of 56 clinically healthy persons with no history of syphilis and negative VDRL tests but reactive fluorescent treponemal antibody absorption (FTA-ABS) tests, 20 spontaneously developed…
TPHA and RPL tests for yaws antibodies.
- MedicineThe British journal of venereal diseases
- 1974
A different group of Pacific Islanders have been screened with these treponemal tests, irrespective of reagin test results, to see if they are preferable to the reagin tests in dianostic screening or epidemiological studies.
The microhemagglutination assay for Treponema pallidum antibodies (MHA-TP), a new treponemal test for syphilis: where does it fit?
- Biology, MedicineJournal of the American Venereal Disease Association
- 1976
The MHA-TP test seems to combine the simplicity and lower cost of nontreponemal tests and the sensitivity and specificity of treponemals tests, and thus enjoys features of both a screening and verification procedure, but additional clinical experience is needed before its role in the serologic diagnosis of syphilis can be conclusively determined.
Hemagglutination tests and related advances in serodiagnosis of syphilis.
- Medicine, BiologyArchives of dermatology
- 1974
Preliminary studies indicate that hemagglutination tests for Treponema pallidum antibodies compare favorably with the fluorescent treponemal antibody absorption (FTA-ABS) test for serodiagnosis of…
The laboratory diagnosis of syphilis. New concepts.
- Medicine, BiologyAnnals of internal medicine
- 1975
The value of modified FTA tests in the diagnosis of neurosyphilis and congenital syphilis remains unproved.
The Treponema Pallidum Haemagglutination test as a screening procedure in the diagnosis of syphilis
- Medicine, BiologyIrish journal of medical science
- 1977
The TPHA test has proved to be more reliable than either the WR or the VDRL test, giving fewer false positive and false negative results by comparison with the FTA-ABS test.
Evaluation of the Treponema pallidum haemagglutination (TPHA) test for syphilis on problem sera
- Acta dermatovenereologica,
- 1974