Specificity of the E. coli LysR-Type Transcriptional Regulators

@inproceedings{Knapp2010SpecificityOT,
  title={Specificity of the E. coli LysR-Type Transcriptional Regulators},
  author={Gwendowlyn S. Knapp and James C. Hu},
  booktitle={PloS one},
  year={2010}
}
BACKGROUND Families of paralogous oligomeric proteins are common in biology. How the specificity of assembly evolves is a fundamental question of biology. The LysR-Type Transcriptional Regulators (LTTR) form perhaps the largest family of transcriptional regulators in bacteria. Because genomes often encode many LTTR family members, it is assumed that many distinct homooligomers are formed simultaneously in the same cell without interfering with each other's activities, suggesting specificity in… CONTINUE READING

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