Specificity of rat T cell receptor V beta chain usage in proliferative responses to staphylococcal enterotoxin B.


The staphylococcal enterotoxins (SE) are potent stimulators of T cell proliferative responses in humans and in mice. In these systems, the toxins function as superantigens and stimulate T cells bearing particular V beta. Although homology between the V beta of mice and humans is limited, related V beta families may respond to certain SE in a similar fashion… (More)