Specificity of junctional communication between animal cells

@article{Pitts1976SpecificityOJ,
  title={Specificity of junctional communication between animal cells},
  author={John D. Pitts and Robert R. Burk},
  journal={Nature},
  year={1976},
  volume={264},
  pages={762-764}
}
MANY types of animal cells, in culture and in vivo, form intercellular junctions which are freely permeable to small cellular ions and molecules but not to macromolecules1–10. These junctions are probably the gap junctions seen by electron microscopy11. Cells coupled by such junctions share their metabolites and small control molecules and respond jointly to changing demands on metabolism. Intercellular control of enzymic activity12,13 and metabolic interdependence causing controlled cell… CONTINUE READING
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