Specificity of infant digestive conditions: some clues for developing relevant in vitro models.

@article{Bourlieu2014SpecificityOI,
  title={Specificity of infant digestive conditions: some clues for developing relevant in vitro models.},
  author={Claire Bourlieu and Olivia M{\'e}nard and Karima Bouzerzour and Giuseppina Mandalari and Adam Macierzanka and Alan R Mackie and Didier Dupont},
  journal={Critical reviews in food science and nutrition},
  year={2014},
  volume={54 11},
  pages={1427-57}
}
Digestion of nutrients is an essential function of the newborn infant gut to allow growth and development and understanding infant digestive function is essential to optimize nutrition and oral drug delivery. Ethical considerations prohibit invasive in vivo trials and as a consequence in vitro assays are often conducted. However, the choice of in vitro model parameters are not supported by an exhaustive analysis of the literature and do not mimic precisely the digestive conditions of the infant… CONTINUE READING
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