Specificity of antibodies to single-stranded (ss) DNA in SLE patients with anti-phospholipid syndrome.

@article{Kaburaki1992SpecificityOA,
  title={Specificity of antibodies to single-stranded (ss) DNA in SLE patients with anti-phospholipid syndrome.},
  author={Junichi Kaburaki and Masataka Kuwana and Takashi Ogasawara and Mayuko Takano and Yoko Funatsu and Tadashi Tojo},
  journal={The Keio journal of medicine},
  year={1992},
  volume={41 1},
  pages={10-5}
}
Although the concept of anti-phospholipid syndrome has been proposed in patients with SLE and other rheumatic diseases, the immunological mechanism is still controversial. Recently, the crossreactivity between anti-cardiolipin antibody and anti-ssDNA antibodies has been discussed in relation to this syndrome. In the present study, the specificity such as the avidity and the crossreactivity of anti-ssDNA antibodies was examined to find a clue to clarify the question why all of anti-cardiolipin… CONTINUE READING