Specificity of a DNA-based (DNAzyme) peroxidative biocatalyst

  title={Specificity of a DNA-based (DNAzyme) peroxidative biocatalyst},
  author={Antonia M. Rojas and Pedro Abreu Gonz{\'a}lez and Eugene Antipov and Alexander M. Klibanov},
  journal={Biotechnology Letters},
A complex formation between hemin and a congruous oligonucleotide not only greatly enhances the former’s peroxidative activity but also results in a biocatalyst (DNAzyme) with a novel specificity. Herein substrate, regio-, enantiomeric, and diastereomeric selectivities of heme, the DNAzyme, and the enzyme horseradish peroxidase are comparatively examined. 

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