Specificity of Legionella pneumophila and Coxiella burnetii vacuoles and versatility of Legionella pneumophila revealed by coinfection.

@article{Sauer2005SpecificityOL,
  title={Specificity of Legionella pneumophila and Coxiella burnetii vacuoles and versatility of Legionella pneumophila revealed by coinfection.},
  author={John-Demian Sauer and Jeffrey G. Shannon and Dale Howe and Stanley F. Hayes and Michele S Swanson and Robert A Heinzen},
  journal={Infection and immunity},
  year={2005},
  volume={73 8},
  pages={4494-504}
}
Legionella pneumophila and Coxiella burnetii are phylogenetically related intracellular bacteria that cause aerosol-transmitted lung infections. In host cells both pathogens proliferate in vacuoles whose biogenesis displays some common features. To test the functional similarity of their respective intracellular niches, African green monkey kidney epithelial (Vero) cells, A/J mouse bone marrow-derived macrophages, human macrophages, and human dendritic cells (DC) containing mature C. burnetii… CONTINUE READING

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