Specificity in killing pathogens is mediated by distinct repertoires of human neutrophil peptides.

Abstract

Neutrophil-derived antimicrobial peptides and proteins (AMPs) play an important role in the defense against microbes. Absence of defense is illustrated by neutropenic patients with frequent bacterial and fungal infections. However, the specificity of the antimicrobial effects has not been adequately described. We set out to determine the specific… (More)
DOI: 10.1159/000317665

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