Specificity and modulation of the action of lactoferrin, a negative feedback regulator of myelopoiesis.

@article{Broxmeyer1980SpecificityAM,
  title={Specificity and modulation of the action of lactoferrin, a negative feedback regulator of myelopoiesis.},
  author={Hal E. Broxmeyer and M Desousa and A M Smithyman and Peter Ralph and Julie Hamilton and J I Kurland and John Bognacki},
  journal={Blood},
  year={1980},
  volume={55 2},
  pages={324-33}
}
The functional capacity of lactoferrin (IF) to act as a negative feedback regulator of myelopoiesis has been investigated and shown to depend on the structure of the molecule itself and on the presence and absence of agents that can modulate its activity. LF has a specific requirement for iron (Fe) in terms of its functional capacity and is most effective in inhibiting the production of granulocyte-macrophage colony stimulating activity (GM-CSA) from monocytes and macrophages when it is fully… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 29 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 38 references

Similar Papers

Loading similar papers…