Specificity and editing by apoptosis of virus-induced cytotoxic T lymphocytes.

@article{Selin1994SpecificityAE,
  title={Specificity and editing by apoptosis of virus-induced cytotoxic T lymphocytes.},
  author={Liisa K. Selin and Raymond M. Welsh},
  journal={Current opinion in immunology},
  year={1994},
  volume={6 4},
  pages={553-9}
}
Recent studies have defined an immunological network by which the acute cytotoxic T-lymphocyte response to viral infection modulates or is modulated by the antigen load and by crossreactive memory T cells. Down regulation of the acute CTL response can be associated with either antigen-dependent or antigen-independent apoptosis, and the host enters a state of immune deficiency as these T cells become sensitized to apoptotic mechanisms. 

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