Specificity, flexibility and valence of DNA bonds guide emulsion architecture

  title={Specificity, flexibility and valence of DNA bonds guide emulsion architecture},
  author={Lang Feng and L{\'e}a-Laetitia Pontani and R{\'e}mi Dreyfus and Paul M. Chaikin and Jasna Bruji{\'c}},
The specificity and thermal reversibility of DNA interactions have enabled the self-assembly of crystal structures, self-replicating materials and colloidal molecules. Grafting DNA onto liquid interfaces of emulsions leads to exciting new architectural possibilities due to the mobility of the DNA ligands and the patches they form between bound droplets. Here we show that the size and number of these adhesion patches (valency) can be controlled. Valence 2 leads to flexible polymers of emulsion… Expand

Figures from this paper

DNA self-organization controls valence in programmable colloid design
This work demonstrates how mobile DNA linkers self-organize at the interface between colloidal droplets into a well-defined number of adhesive patches, that is, valence, to create order on much longer length scales. Expand
Volume and porosity thermal regulation in lipid mesophases by coupling mobile ligands to soft membranes
A model providing a thorough understanding of the thermal response of pairs and networks of DNA-tethered liposomes is developed, explaining the emergent properties out of the interplay between the temperature-dependent deformability of the vesicles and the DNA-mediated adhesive forces. Expand
Entropy Stabilizes Floppy Crystals of Mobile DNA-Coated Colloids.
It is demonstrated that these floppy phases are stabilized by vibrational entropy, and "floppy" modes play an important role in stabilizing the floppy phases for the infinite binding strength limit. Expand
Using DNA strand displacement to control interactions in DNA-grafted colloids.
The method allows us to make multicomponent systems that can self-assemble over a wide range of temperatures, invert the dependence on temperature to design colloidal systems that melt upon cooling, controllably transition between structures with different compositions, or design systems with multiple melting transitions. Expand
Surface-triggered cascade reactions between DNA linkers direct the self-assembly of colloidal crystals of controllable thickness.
This work presents a system in which functionalized surfaces initiate a cascade reaction between linkers leading to the self-assembly of crystals with a controllable number of layers, and suggests a new avenue to fabricate heterogeneous and finite structures. Expand
Specific and Reversible DNA-Directed Self-Assembly of Modular Vesicle-Droplet Hybrid Materials.
This work functionalized giant unilamellar vesicles and emulsion droplets with biotinylated single-stranded DNA oligonucleotides using streptavidin as an intermediary linker to demonstrate specific and reversible DNA-directed self-assembly into vesicle-droplet hybrid structures. Expand
Understanding the Self-Assembly of DNA-Coated Colloids via Theory and Simulations
Abstract DNA-coated colloids (DNACCs) are one of the most exciting systems for the programmable self-assembly of colloidal structures. Their versatility arises naturally from the selectivity andExpand
Self-assembly and crystallization of DNA-coated colloids via linker-encoded interactions.
It is shown that linker-mediated interactions direct the self-assembly of colloids into equilibrium crystal structures, and it is found that asymmetry strongly influences the concentration dependence of the colloidal interactions, which is explained using a mean-field model. Expand
Oligonucleotide-based recognition in colloidal systems - opportunities and challenges
Abstract DNA-functionalized colloidal particles have wide-spanning applicability from biotechnology to nanotechnology. Within the colloids community, there is a rich experimental and theoreticalExpand
Freely Jointed Polymers Made of Droplets.
This work controls the valence of DNA-functionalized emulsions to make linear and branched model polymers, or "colloidomers," which can be repeatedly assembled and disassembled under temperature cycling, allowing for reconfigurable, responsive matter. Expand