Specificities of secretion and uptake of exosomes and other extracellular vesicles for cell-to-cell communication

  title={Specificities of secretion and uptake of exosomes and other extracellular vesicles for cell-to-cell communication},
  author={M. Mathieu and Lorena Martin-Jaular and Gr{\'e}gory Lavieu and C. Th{\'e}ry},
  journal={Nature Cell Biology},
  • M. Mathieu, Lorena Martin-Jaular, +1 author C. Théry
  • Published 2019
  • Chemistry, Medicine
  • Nature Cell Biology
  • The ability of exosomes to transfer cargo from donor to acceptor cells, thereby triggering phenotypic changes in the latter, has generated substantial interest in the scientific community. However, the extent to which exosomes differ from other extracellular vesicles in terms of their biogenesis and functions remains ill-defined. Here, we discuss the current knowledge on the specificities of exosomes and other types of extracellular vesicles, and their roles as important agents of cell-to-cell… CONTINUE READING
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