Specification of regions of DNA replication initiation during embryogenesis in the 65-kilobase DNApolalpha-dE2F locus of Drosophila melanogaster.

Abstract

In the early stage of Drosophila embryogenesis, DNA replication initiates at unspecified sites in the chromosome. In contrast, DNA replication initiates in specified regions in cultured cells. We investigated when and where the initiation regions are specified during embryogenesis and compared them with those observed in cultured cells by two-dimensional… (More)

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@article{Sasaki1999SpecificationOR, title={Specification of regions of DNA replication initiation during embryogenesis in the 65-kilobase DNApolalpha-dE2F locus of Drosophila melanogaster.}, author={Toru Sasaki and Tomoyuki Sawado and M Yamaguchi and T. Shinomiya}, journal={Molecular and cellular biology}, year={1999}, volume={19 1}, pages={547-55} }