Specification of layer-specific connections in the developing cortex.

  title={Specification of layer-specific connections in the developing cortex.},
  author={Jan Bolz and Valerie Castellani and Fanny Mann and Sigrid Henke-Fahle},
  journal={Progress in brain research},
One of the basic tasks of neurobiology is to understand how the precision and specificity of neuronal connections is achieved during development. In this paper we reviewed some recent in vitro studies on the developing mammalian cerebral cortex that have been made towards this end. The results of these experiments provided evidence that membrane-associated molecules are instrumental for the formation of specific afferent and efferent cortical projections. Substrate-bound molecules guide growing… CONTINUE READING


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