Specification of C/EBP function during Drosophila development by the bZIP basic region.

@article{Rrth1994SpecificationOC,
  title={Specification of C/EBP function during Drosophila development by the bZIP basic region.},
  author={P R\orth},
  journal={Science},
  year={1994},
  volume={266 5192},
  pages={1878-81}
}
The biologically relevant interactions of a transcription factor are those that are important for function in the organism. Here, a transgenic rescue assay was used to determine which molecular functions of Drosophila CCAAT/enhancer binding protein (C/EBP), a basic region-leucine zipper transcription factor, are required for it to fulfill its essential role during development. Chimeric proteins that contain the Drosophila C/EBP (DmC/EBP) basic region, a heterologous zipper, and a heterologous… CONTINUE READING