Specific staining of human chromosomes in Chinese hamster x man hybrid cell lines demonstrates interphase chromosome territories

@article{Schardin2004SpecificSO,
  title={Specific staining of human chromosomes in Chinese hamster x man hybrid cell lines demonstrates interphase chromosome territories},
  author={M. Schardin and T. Cremer and H. Hager and M. Lang},
  journal={Human Genetics},
  year={2004},
  volume={71},
  pages={281-287}
}
SummaryIn spite of Carl Rabl's (1885) and Theodor Boveri's (1909) early hypothesis that chromosomes occupy discrete territories or domains within the interphase nucleus, evidence in favor pf this hypothesis has been limited and indirect so far in higher plants and animals. The alternative possibility that the chromatin fiber of single chromosomes might be extended throughout the major part of even the whole interphase nucleus has been considered for many years. In the latter case, chromosomes… Expand
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