Specific species of intestinal bacteria influence the induction of aberrant crypt foci by 1,2-dimethylhydrazine in rats.

Abstract

To shed light on the association of intestinal microflora with the development of colon cancer, we studied the modifying effects of intestinal microflora on the occurrence of 1,2-dimethylhydrazine (DMH)-induced colonic aberrant crypt foci (ACF) in germfree (GF), gnotobiotic (GB) and conventionalized (Cvd) rats. In the first part of this study, 10 week old… (More)

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@article{Onoue1997SpecificSO, title={Specific species of intestinal bacteria influence the induction of aberrant crypt foci by 1,2-dimethylhydrazine in rats.}, author={Masaharu Onoue and Shoichi Kado and Y Sakaitani and Kazuyuki Uchida and Masami Morotomi}, journal={Cancer letters}, year={1997}, volume={113 1-2}, pages={179-86} }