Specific role of the posterior dorsal hippocampus-prefrontal cortex in short-term working memory.

@article{Izaki2008SpecificRO,
  title={Specific role of the posterior dorsal hippocampus-prefrontal cortex in short-term working memory.},
  author={Yoshinori Izaki and Masatoshi Takita and Tatsuo Akema},
  journal={The European journal of neuroscience},
  year={2008},
  volume={27 11},
  pages={
          3029-34
        }
}
Working memory in rats involves neural projections from the hippocampus (HP) to the prefrontal cortex (PFC), based on delayed task experiments in a radial-arm maze, in which the time span of working memory is longer than seconds. To determine whether the HP-PFC pathway is involved in short-term (on the order of seconds) working memory function, we lesioned the PFC and/or HP, and measured performance in an operant delayed alternation task. The posterior dorsal (pdHP) and ventral HP (vHP) were… CONTINUE READING
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