Specific residues of a conserved domain in the N terminus of the human cytomegalovirus pUL50 protein determine its intranuclear interaction with pUL53.

@article{Milbradt2012SpecificRO,
  title={Specific residues of a conserved domain in the N terminus of the human cytomegalovirus pUL50 protein determine its intranuclear interaction with pUL53.},
  author={Jens Milbradt and Sabrina Auerochs and Madhumati Sevvana and Yves A Muller and Heinrich Sticht and Manfred Marschall},
  journal={The Journal of biological chemistry},
  year={2012},
  volume={287 28},
  pages={24004-16}
}
Herpesviral capsids are assembled in the host cell nucleus and are subsequently translocated to the cytoplasm. During this process it has been demonstrated that the human cytomegalovirus proteins pUL50 and pUL53 interact and form, together with other viral and cellular proteins, the nuclear egress complex at the nuclear envelope. In this study we provide… CONTINUE READING