Specific regions of Escherichia coli OmpF protein involved in antigenic and colicin receptor sites and in stable trimerization.

Abstract

Four different mutations were obtained by selecting for resistance to colicin N and screening for continued production of the OmpF protein of Escherichia coli. Two of them also conferred resistance to colicin A. The substitutions C for R-168 (R168C) and E284K caused the loss of the E21 epitope, while the transition G285D altered the E18, E19, and E20… (More)

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