Specific reduction of carboxyl groups in peptides and proteins by diborane.

Abstract

1. The reaction of several peptides and proteins with diborane was studied under different conditions to determine those most suitable for the specific reduction of carboxyl groups. 2. In the reaction of model peptides and the cyclic peptides bacitracin and tyrocidin, reduction at 0 degrees was entirely specific for the carboxyl groups without affecting the… (More)

Topics

Cite this paper

@article{Atassi1969SpecificRO, title={Specific reduction of carboxyl groups in peptides and proteins by diborane.}, author={M. Zouhair Atassi and Arthur F. Rosenthal}, journal={The Biochemical journal}, year={1969}, volume={111 4}, pages={593-601} }