Specific oxidative cleavage of carotenoids by VP14 of maize.

  title={Specific oxidative cleavage of carotenoids by VP14 of maize.},
  author={Steven H. Schwartz and Boon Chin Tan and Douglas A. Gage and Jan A. D. Zeevaart and Donald R McCarty},
  volume={276 5320},
The plant growth regulator abscisic acid (ABA) is formed by the oxidative cleavage of an epoxy-carotenoid. The synthesis of other apocarotenoids, such as vitamin A in animals, may occur by a similar mechanism. In ABA biosynthesis, oxidative cleavage is the first committed reaction and is believed to be the key regulatory step. A new ABA-deficient mutant of maize has been identified and the corresponding gene, Vp14, has been cloned. The recombinant VP14 protein catalyzes the cleavage of 9-cis… CONTINUE READING
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