Specific oxidative alterations in vastus lateralis muscle of patients with the diagnosis of chronic fatigue syndrome.

@article{Fulle2000SpecificOA,
  title={Specific oxidative alterations in vastus lateralis muscle of patients with the diagnosis of chronic fatigue syndrome.},
  author={Stefania Fulle and Patrizia Mecocci and Giorgio Fan{\'o} and I Vecchiet and Alba Vecchini and D Racciotti and Antonio Cherubini and Eligio Pizzigallo and Leonardo Vecchiet and Umberto Senin and Myron Flint Beal},
  journal={Free radical biology & medicine},
  year={2000},
  volume={29 12},
  pages={1252-9}
}
Chronic fatigue syndrome (CFS) is a poorly understood disease characterized by mental and physical fatigue, most often observed in young white females. Muscle pain at rest, exacerbated by exercise, is a common symptom. Although a specific defect in muscle metabolism has not been clearly defined, yet several studies report altered oxidative metabolism. In this study, we detected oxidative damage to DNA and lipids in muscle specimens of CFS patients as compared to age-matched controls, as well as… CONTINUE READING
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