Specific localization of membrane dipeptidase and dipeptidyl peptidase IV in secretion granules of two different pancreatic islet cells.

@article{Grondin1999SpecificLO,
  title={Specific localization of membrane dipeptidase and dipeptidyl peptidase IV in secretion granules of two different pancreatic islet cells.},
  author={Gilles Grondin and Nigel M Hooper and Denis Lebel},
  journal={The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society},
  year={1999},
  volume={47 4},
  pages={489-98}
}
Endocrine cells require several protein convertases to process the precursors of hormonal peptides that they secrete. In addition to the convertases, which have a crucial role in the maturation of prohormones, many other proteases are present in endocrine cells, the roles of which are less well established. Two of these proteases, dipeptidyl peptidase IV (EC 3.4.14.5) and membrane dipeptidase (EC 3.4.13.19), have been immunocytochemically localized in the endocrine pancreas of the pig. Membrane… CONTINUE READING

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