Specific insulin binding by, and imprintability of, the nuclear membrane of Tetrahymena.

@article{Hegyesi1992SpecificIB,
  title={Specific insulin binding by, and imprintability of, the nuclear membrane of Tetrahymena.},
  author={Hargita Hegyesi and Gy{\"o}rgy Csaba},
  journal={Cytobios},
  year={1992},
  volume={72 290-291},
  pages={153-7}
}
Cellular nuclei isolated from Tetrahymena were able to bind FITC-labelled insulin, and pretreatment with different concentrations of unlabelled insulin accounted for a decrease in FITC-insulin binding of the nuclear membrane. This strongly suggests an association of specific insulin receptors with the nuclear envelope of Tetrahymena. Nuclei isolated 1 week after primary exposure of Tetrahymena cells to insulin showed a 50% binding increase over the controls. This supports the implication that… CONTINUE READING

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