Specific impairment of proximal tubular cell proliferation by a monoclonal κ light chain responsible for Fanconi syndrome.

Abstract

BACKGROUND Fanconi syndrome (FS) is a rare renal disorder featuring proximal tubule dysfunction that may occur following tubular reabsorption of a monoclonal light chain (LC), in patients with multiple myeloma. FS may precede the recognition of multiple myeloma by several years. In most cases, crystalline inclusions of monoclonal κ LCs are observed within… (More)
DOI: 10.1093/ndt/gfs261

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Cite this paper

@article{Hamel2012SpecificIO, title={Specific impairment of proximal tubular cell proliferation by a monoclonal κ light chain responsible for Fanconi syndrome.}, author={Chahrazed El Hamel and Jean-Claude Aldigier and Christelle Oblet and Brice Laffleur and Frank Bridoux and Michel Cogn{\'e}}, journal={Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association}, year={2012}, volume={27 12}, pages={4368-77} }