Specific immunotherapy prevents increased levels of allergen-specific IL-4- and IL-13-producing cells during pollen season.

@article{Gabrielsson2001SpecificIP,
  title={Specific immunotherapy prevents increased levels of allergen-specific IL-4- and IL-13-producing cells during pollen season.},
  author={Susanne Gabrielsson and Atle S{\"o}derlund and Staffan Paulie and Tineke C. T. M. van der Pouw Kraan and Marita Troye-Blomberg and Sabina Rak},
  journal={Allergy},
  year={2001},
  volume={56 4},
  pages={293-300}
}
BACKGROUND Specific allergen immunotherapy (SIT) is effective for treatment of IgE-mediated diseases: however, the mechanisms of action still remain unclear. Earlier, we showed that IL-4 and IL-13 are produced in response to specific allergens. The aim of this study was to investigate whether these cytokine responses were affected by allergen SIT, and, furthermore, to evaluate the effect of SIT on allergen-specific IgE and IgG4 levels. METHODS Blood samples from pollen-sensitized individuals… CONTINUE READING