Specific heterologous antimacrophage serum: In vitro effects, and the effect on the efferent arm of cutaneous delayed hypersensitivity

@article{Smith1972SpecificHA,
  title={Specific heterologous antimacrophage serum: In vitro effects, and the effect on the efferent arm of cutaneous delayed hypersensitivity},
  author={Stanley B. Smith and Edwin Pont},
  journal={Blut: Zeitschrift f{\"u}r die Gesamte Blutforschung},
  year={1972},
  volume={24},
  pages={236-246}
}
A heterologous rabbit anti-rat macrophage serum was prepared which showed cross-reactions with both rat erythrocytes and rat thymocytes. After sequential absorptions a specific antimacrophage serum was prepared, which did not show agglutination or cytotoxicity for rat thymocytes or lymph node cells. This specific AMS was cytotoxic for macrophages and… CONTINUE READING