Specific gene expression and possible involvement of inflammation in methamphetamine-induced neurotoxicity.

@article{Asanuma2004SpecificGE,
  title={Specific gene expression and possible involvement of inflammation in methamphetamine-induced neurotoxicity.},
  author={Masato Asanuma and Ikuko Miyazaki and Youichirou Higashi and Takeshi Tsuji and Norio Ogawa},
  journal={Annals of the New York Academy of Sciences},
  year={2004},
  volume={1025},
  pages={69-75}
}
To reveal specific gene expression in methamphetamine (METH) -induced dopamine neurotoxicity, temporal characteristics of METH-induced changes in gene expression in dopaminergic neuronal cells were examined using the cDNA array and the differential display method. A number of genes in the class of "trafficking & protein turnover," "metabolic pathways," "transmitters & receptors," and "growth factors, cytokines" were upregulated after the METH treatment in the cDNA array assay. Whereas, some… CONTINUE READING

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