Specific gamma‐aminobutyrate chemotaxis in pseudomonads with different lifestyle

  title={Specific gamma‐aminobutyrate chemotaxis in pseudomonads with different lifestyle},
  author={J. Reyes-Darias and V. Garc{\'i}a and Miriam Rico-Jim{\'e}nez and A. Corral-Lugo and O. Lesouhaitier and Dalia Ju{\'a}rez-Hern{\'a}ndez and Yiling Yang and Shuangyu Bi and M. Feuilloley and J. Mu{\~n}oz-Rojas and V. Sourjik and T. Krell},
  journal={Molecular Microbiology},
  • J. Reyes-Darias, V. García, +9 authors T. Krell
  • Published 2015
  • Biology, Medicine
  • Molecular Microbiology
  • The PctC chemoreceptor of Pseudomonas aeruginosa mediates chemotaxis with high specificity to gamma-aminobutyric acid (GABA. [...] Key Result We report the identification of McpG as a specific GABA chemoreceptor in non-pathogenic Pseudomonas putida KT2440. As with PctC, GABA was found to bind McpG tightly. The analysis of chimeras comprising the PctC and McpG ligand-binding domains fused to the Tar signaling domain showed very high GABA sensitivities.Expand Abstract
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