Specific electropermeabilization of leucocytes in a blood sample and application to large volumes of cells.

@article{Sixou1990SpecificEO,
  title={Specific electropermeabilization of leucocytes in a blood sample and application to large volumes of cells.},
  author={S. Sixou and Justin Teissi{\'e}},
  journal={Biochimica et biophysica acta},
  year={1990},
  volume={1028 2},
  pages={154-60}
}
Electropermeabilization is obtained when the membrane potential difference reaches a critical threshold. This is performed by submitting cells to an external electric field pulse. The field modulates the endogenous potential difference in a cell-size-dependent way. Computer simulations predict that large cells would be specifically permeabilized in a mixture with smaller cells. This was examined on a mixture of Chinese hamster ovary (CHO) cells and erythrocytes. CHO cells were permeabilized to… CONTINUE READING

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