Specific dietary polyphenols attenuate atherosclerosis in apolipoprotein E-knockout mice by alleviating inflammation and endothelial dysfunction.

@article{Loke2010SpecificDP,
  title={Specific dietary polyphenols attenuate atherosclerosis in apolipoprotein E-knockout mice by alleviating inflammation and endothelial dysfunction.},
  author={Wai Mun Loke and Julie M. Proudfoot and Jonathan M Hodgson and Allan J McKinley and Neil Hime and Maria Magat and Roland Stocker and Kevin D Croft},
  journal={Arteriosclerosis, thrombosis, and vascular biology},
  year={2010},
  volume={30 4},
  pages={749-57}
}
OBJECTIVE Animal and clinical studies have suggested that polyphenols in fruits, red wine, and tea may delay the development of atherosclerosis through their antioxidant and anti-inflammatory properties. We investigated whether individual dietary polyphenols representing different polyphenolic classes, namely quercetin (flavonol), (-)-epicatechin (flavan-3-ol), theaflavin (dimeric catechin), sesamin (lignan), or chlorogenic acid (phenolic acid), reduce atherosclerotic lesion formation in the… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 92 extracted citations

Proatherogenic macrophage activities are targeted by the flavonoid quercetin.

The Journal of pharmacology and experimental therapeutics • 2012
View 5 Excerpts
Highly Influenced

Hypolipidemic and Antioxidant Effects of Black Tea Extract and Quercetin in Atherosclerotic Rats

Wahyu Widowati, Hana Ratnawati, Tjandrawati Mozefis, Dwiyati Pujimulyani, A YellianttyYelliantty
2013
View 3 Excerpts
Highly Influenced

Time-dependent beneficial effect of chronic polyphenol treatment with catechin on endothelial dysfunction in aging mice.

Dose-response : a publication of International Hormesis Society • 2012
View 2 Excerpts
Highly Influenced

Flavonols and cardiovascular disease.

Molecular aspects of medicine • 2010
View 5 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…