Specific cytolytic T-cell responses to human CEA from patients immunized with recombinant avipox-CEA vaccine.

@article{Zhu2000SpecificCT,
  title={Specific cytolytic T-cell responses to human CEA from patients immunized with recombinant avipox-CEA vaccine.},
  author={M. Z. Zhu and J Marshall and Diane Cole and Jeffrey Schlom and Kwong Yok Tsang},
  journal={Clinical cancer research : an official journal of the American Association for Cancer Research},
  year={2000},
  volume={6 1},
  pages={24-33}
}
Avipox viruses are replication-defective members of the poxvirus family. Avipox-derived vectors such as ALVAC (canarypox) and fowlpox have the ability to infect mammalian cells, including human cells, but do not replicate. The first clinical trial of an avipox recombinant vaccine for patients with advanced carcinomas has recently been conducted using the… CONTINUE READING