Specific complexation of disaccharides with diphenyl-3,3′-diboronic acid that can be detected by circular dichroism

  title={Specific complexation of disaccharides with diphenyl-3,3′-diboronic acid that can be detected by circular dichroism},
  author={K. Kondo and Y. Shiomi and Miwako Saisho and T. Harada and S. Shinkai},
Abstract For the development of new receptor molecules that can recognize sugar molecules, we synthesized diphenyl-3,3′-diboronic acid (2). The distance between the two boronic acids in 2 is designed so that it can selectively form cyclic 1:1 complexes with disaccharides. It was shown that 2 forms 1:1 complexes with several disaccharides and gives the characteristic exciton coupling in CD spectroscopy owing to immobilization of the two phenyl rings. Thus, the absolute configuration was… Expand
105 Citations
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