Specific chromosome aberration in human renal cell carcinoma.

  title={Specific chromosome aberration in human renal cell carcinoma.},
  author={Gyula Kov{\'a}cs and Sandor Sz{\"u}cs and W de Riese and Helmut Baumg{\"a}rtel},
  journal={International journal of cancer},
  volume={40 2},
Using G-banding technique, the chromosomes were studied in short-term cultures of 25 primary renal-cell carcinomas (RCC). Phytohaemagglutinin-stimulated peripheral blood lymphocytes or normal kidney cells of the same patients growing in primary cultures were analysed to define the constitutional karyotype. The modal chromosome number of 23 RCC's was found to be pseudo-diploid or near-diploid with only few structural rearrangements, 22 of the RCC's showed an aberration of chromosome 3, deletion… CONTINUE READING