Specific binding of a cellular DNA replication protein to the origin of replication of adenovirus DNA.

@article{Nagata1983SpecificBO,
  title={Specific binding of a cellular DNA replication protein to the origin of replication of adenovirus DNA.},
  author={Kyosuke Nagata and R A Guggenheimer and Jerard Hurwitz},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1983},
  volume={80 20},
  pages={6177-81}
}
Nuclear factor I, a 47-kilodalton protein, purified from nuclear extracts of uninfected HeLa cells, is involved in the initiation and possibly the elongation of replicating adenovirus (Ad) DNA in vitro. The binding of nuclear factor I to DNA has been monitored by a filter binding assay of nuclear factor I to DNA has been monitored by a filter binding assay using plasmid pLA1 DNA, which contains a 3,290 base-pair fragment derived from the left-hand terminus (coordinates, 0-9.4 map units) of Ad… CONTINUE READING