Specific autoantibody slows the rapid plasma clearance of 125I-SS-B (La) in mice.

Abstract

In BALB/c mice the plasma clearance of intravenously (i.v.) injected 125I-SS-B (La) (T 1/2 = 3 min) is markedly delayed when complexed in vitro to specific autoantibody (T 1/2 = 60 min) and is associated with diminished hepatic and renal uptake. The in vivo behaviour of 11S 125I-SS-B-IgG-anti-SS-B complexes was similar to that of 20-30S 125I-heat-aggregated… (More)

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@article{Schrieber1984SpecificAS, title={Specific autoantibody slows the rapid plasma clearance of 125I-SS-B (La) in mice.}, author={Leslie Schrieber and Richard D Melsom and P. J. W. Venables and Desmond A McCarthy and Ravinder N. Maini}, journal={Clinical and experimental immunology}, year={1984}, volume={56 3}, pages={621-7} }