Specific and non-overlapping functions of testosterone and 11-ketotestosterone in the regulation of professional phagocyte responses in the teleost fish gilthead seabream.

@article{guila2013SpecificAN,
  title={Specific and non-overlapping functions of testosterone and 11-ketotestosterone in the regulation of professional phagocyte responses in the teleost fish gilthead seabream.},
  author={Sergio {\'A}guila and Patricia Castillo-Brice{\~n}o and Massimo Sanchez and Isabel Cabas and Alicia Garc{\'i}a-Alc{\'a}zar and Jose Jaime Meseguer and Victoriano Mulero and Alfonsa Garc{\'i}a-Ayala},
  journal={Molecular immunology},
  year={2013},
  volume={53 3},
  pages={218-26}
}
Sex hormones, both estrogens and androgens, have a strong impact on immunity in mammals. In fish, the role of androgens in immunity has received little attention and contradictory conclusions have been obtained. However, it is well known that sex steroids are involved in fish growth, osmoregulation and gonad remodelation. In this study, we examine the in vitro effects of testosterone and 11-ketotestosterone, the two main fish androgens, on the professional phagocytes of the teleost fish… CONTINUE READING
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