Specific and high-level targeting of radiolabeled octreotide analogues to human medulloblastoma xenografts.

Abstract

PURPOSE The objective of this study was to determine the feasibility of exploiting the overexpression of somatostatin subtype-2 receptors (sstr(2)) on human medulloblastoma cells to develop targeted radiodiagnostics and radiotherapeutics for this disease. EXPERIMENTAL DESIGN The following radioiodinated peptides were prepared using chloramine-T and… (More)

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