Specific activation of AP-1 but not Stat3 in regenerating liver in mice.

@article{Heim1997SpecificAO,
  title={Specific activation of AP-1 but not Stat3 in regenerating liver in mice.},
  author={Markus H Heim and Gerdien Gamboni and Christoph Beglinger and Klaus E. Gyr},
  journal={European journal of clinical investigation},
  year={1997},
  volume={27 11},
  pages={
          948-55
        }
}
Liver regeneration following partial hepatectomy is regulated by hepatotrophic factors whose precise roles are still elusive. In cell culture studies, some of them have been shown to activate members of the family of the signal transducers and activators of transcription (Stat). To test this contention in vivo, nuclear extracts were isolated from livers of partially hepatectomized and sham-operated mice killed at 30 different time points between zero and 108 h after surgery. Stat3 DNA binding… CONTINUE READING

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