Specific Requirements for the Action of Deoxyribonuclease

Abstract

THE mechanism of action of pancreatic deoxyribonuclease, now available in the crystalline state1,2, on highly polymerized deoxypentose nucleic acids is still obscure. The enzymatic attack is known to result in the formation of dialysable oligonucleotides and of a non-dialysable ‘core’ which, in the case of the nucleic acids from calf thymus3,4 and wheat… (More)
DOI: 10.1038/168916a0

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