Specific IgE antibodies to nickel in workers with known reactivity to cobalt.

@article{Shirakawa1992SpecificIA,
  title={Specific IgE antibodies to nickel in workers with known reactivity to cobalt.},
  author={Toshiro Shirakawa and Yukinori Kusaka and Kanehisa Morimoto},
  journal={Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology},
  year={1992},
  volume={22 2},
  pages={213-8}
}
Twenty-one workers with hard metal asthma, including eight atopics, diagnosed on the basis of peak flow diaries and positive reaction to cobalt chloride (CoCl2) and/or nickel sulphate (NiSO4) in skin and provocation tests were studied for sensitization by detection of specific antibodies to nickel-conjugated human serum albumin (Ni-HSA), and nickel-conjugated exchange resin (Ni-resin). Their results were compared with those of sera obtained from control sera from 60 asthmatic patients and pair… CONTINUE READING

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